Specializing in Lipoprotein and Cholesterol metabolism, her PhD focused on sitostanol (a plant sterol) in understanding cholesterol-lowering properties. In addition, Dr. Ramji has also conducted clinical studies to evaluate the effect of dietary cholesterol (from eggs) on lipoprotein metabolism. During her Ph.D., Dr. Ramji established expertise in cholesterol metabolism.
After receiving her Ph.D., Dr. Ramji completed her post-doctoral research training in Cardiovascular Biology where she studies the role of Aortic preferentially expressed gene (APEG) in dilated cardiomyopathy at Brigham and Women’s Hospital, Harvard Medical School, Boston.
Ramjiganesh T, Liu X, Chen YH, Chung SW, Hall SR, Schissel SL, Padera RF Jr, Liao R, Ackerman KG, Kajstura J, Leri A, Anversa P, Yet SF, Layne MD, Perrella MA. Disruption of striated preferentially expressed gene locus leads to dilated cardiomyopathy in mice. Circulation. 2009 Jan 20;119(2):261-8. Epub 2008 Dec 31.
Herron KL, Vega-Lopez S, Conde K, Ramjiganesh T, Shachter NS, Fernandez ML. Men classified as hypo- or hyper responders to dietary cholesterol feeding exhibit differences in lipoprotein metabolism. J Nutr. 2003 Apr;133(4):1036-42.
West KL, Ramjiganesh T, Roy S, Keller BT, Fernandez ML.1-[4-[4[(4R,5R)-3,3-Dibutyl-7- (dimethylamino)-2,3,4,5-tetrahydro-4-hydroxy-1,1-dioxido-1-benzothiepin-5-yl]phenoxy]butyl]-4-aza- 1-azoniabicyclo[2.2.2]octane methanesulfonate (SC-435), an ileal apical sodium-codependent bile acid transporter inhibitor alters hepatic cholesterol metabolism and lowers plasma low-density lipoprotein- cholesterol concentrations in guinea pigs. J Pharmacol Exp Ther. 2002 Oct;303(1):293-9.
Herron KL, Vega-Lopez S, Conde K, Ramjiganesh T, Roy S, Shachter NS, Fernandez ML. Pre-menopausal women, classified as hypo- or hyperresponders, do not alter their LDL/HDL ratio following a high dietary cholesterol challenge. J Am Coll Nutr. 2002 Jun;21(3):250-8.
Ramjiganesh T, Roy S, Freake HC, McIntyre JC, Fernandez ML. Corn fiber oil lowers plasma cholesterol by altering hepatic cholesterol metabolism and up-regulating LDL receptors in guinea pigs. J Nutr. 2002 Mar;132(3):335-40.
Fernandez ML, West KL, Roy S, Ramjiganesh T. Dietary fat saturation and gender/hormonal status modulate plasma lipids and lipoprotein composition. J Nutr Biochem. 2001 Dec;12(12):703-710.
Cos E, Ramjiganesh T, Roy S, Yoganathan S, Nicolosi RJ, Fernandez ML. Soluble fiber and soybean protein reduce atherosclerotic lesions in guinea pigs. Sex and hormonal status determine lesion extension. Lipids. 2001 Nov;36(11):1209-16.
Ramjiganesh T, Roy S, McIntyre JC, Luz Fernandez M. The hypocholesterolaemic effects of sitostanol in the guinea pig are in part related to changes in hepatic lipids and lipoprotein composition. Br J Nutr. 2001 Feb;85(2):165-72.
Ramjiganesh T, Roy S, Nicolosi RJ, Young TL, McIntyre JC, Fernandez ML. Corn husk oil lowers plasma LDL cholesterol concentrations by decreasing cholesterol absorption and altering hepatic cholesterol metabolism in guinea pigs. J Nutr Biochem. 2000 Jul-Aug;11(7-8):358-66.
Ramjiganesh T, Chen YH, Yet SF, Layne MD and Perrella MA. Enhancement of Aortic Preferentially expressed gene-1 by Sp1 and upstream stimulatory factor. American Thoracic Society, Orlando, FL, May 2004.
Ramjiganesh T, Roy S, Freake HC and Fernandez ML. Corn Fiber Oil lowers plasma Cholesterol by altering Hepatic Cholesterol Metabolism. Experimental Biology, Orlando, FL, April 2001.
Ramjiganesh T, Roy S, McIntyre JC and Fernandez ML. Hypocholesterolemic mechanisms of Sitostanol in the Guinea Pig. Experimental Biology, San Diego, CA, April 2000.
Ramjiganesh T, Roy S, Vega-Lopez S, McIntyre JC, and Fernandez ML. Hypocholesterolemic mechanisms of Corn Fiber Oil in the Guinea Pig. Experimental Biology, Washington DC, April 1999